Description
As a member of the R&D Enzymes team in Andenne, the VIE will contribute to the development, optimization, and scale-up of downstream processing technologies for enzymes. The role focuses on separation, concentration, clarification, stabilization, and formulation of enzyme solutions, bridging lab-scale development and industrial implementation.
The VIE will work closely with R&D, Process Development, Quality, Operations, and external partners to ensure robust, scalable, and cost-efficient downstream processes delivering consistent enzyme performance.
Key Accountabilities
Downstream Process Development
• Support and lead R&D projects related to enzyme downstream processing, including filtration, membrane technologies (microfiltration, ultrafiltration, diafiltration), concentration, clarification and microbial removal steps.
• Design, execute, and analyze laboratory and pilot-scale trials for enzyme processing and formulation.
• Contribute to the development and optimization of enzyme stabilization and formulation strategies (liquid formulations, concentrates, intermediates, or dried formats in collaboration with other teams).
• Evaluate process robustness, yield, enzyme activity recovery, and scalability.
Characterization & Data Analysis
• Perform liquid and process stream characterization (activity, protein content, impurities, viscosity, stability, shelf life).
• Build fundamental understanding of the links between upstream material characteristics, downstream processing parameters, and final enzyme recovery.
• Analyze experimental data and translate results into clear technical recommendations.
Scale-up & Industrial Support
• Support scale-up activities from lab to pilot and industrial scale in close collaboration with Operations and Process Improvement teams.
• Participate in industrial trials, tech-transfer to operation and contribute to troubleshooting and continuous improvement of existing downstream processes.
• Quality, Safety & Regulatory Compliance: comply with HACCP and food safety regulations and take part in deviation investigations.
Collaboration & Innovation
• Coordinate and manage interactions with internal stakeholders (R&D, Quality, Purchasing, Operations).
• Contribute to collaborations with external partners and suppliers (membrane manufacturers, equipment suppliers, analytical partners, research institutes).
• Monitor and review scientific literature, patents, and emerging technologies related to enzyme downstream processing.
Documentation & Knowledge Sharing
• Document processes, experimental results, and conclusions in a structured and traceable way.
• Contribute to internal knowledge building through reports, technical notes, and presentations.
• Support the development of training materials and knowledge transfer to operations teams when relevant.